None. No lotion fights the signs of aging.

The only way to do that is to generally look after yourself. Sun cream , healthy balanced diet, plenty of exercise and water.

Good genetics also help

Peanut butter and two rabid dogs

best way to prevent untimely wrinkles is to protect from sun damage, so get a lotion with SPF

Semen they say...

Can’t reverse aging or wrinkles, but we can try to slow it down. Wash with gentle cleansers, keep hydrated by drinking lots of water, and protect from the sun.

Just sit tight, in a few years they will start injecting stem cells or some shit into your face and you're all set

Bull semen. Best facial serum ever. Keeps everything taught.

Slug slime, it's natural and removes all wrinkles, trust me

Probably something rich with fiber and wax, not sure if such thing exists.

None that you can buy. There is a selection of medical products containing strong organic acids that remove part of the skin and causes it to regenerate, but it only can be done under a doctors supervision and not very often. You better start loving wrinkles.