Demon is easily top-tier, since it got most pros of vampirism without the tons of hazards.

A far second is being a vampire, immortality is cool but what's the use if any of the long list of everyday things can instakill you.

Werewolfs don't seem different from normal people, apart having that time of the month. Even without being very aware of it or having any control, apparently. It does jack shit except make life more miserable so no wonder it's referred to as a curse.