IF U MEAN LIKE... OC-WISE...? Rina takes the cake because she is a Literal "Girl Thing" like her body and pronouns and gender appear Feminine but shes not entirely "Human" and quite literally is some sort of Thing so she's definitely the One. though Adele comes real close in clutch due to her situation. Eureka following suit and any angels that present as feminine/girls fall under that definition in virtue of being girls but also things (aka body possessing alien parasites)