I have felt endangered in some ways in NYC, London, Rome, Paris, Hamburg, Frankfurt, Brussels. My fears were rape, robbery, slaughter. I never was in South America, so no clue. But any major city has danger zones, some danger zones are very big. Some mid sized cities are entire danger zones. I have been in Detroit which is a battle zone, at least it was at the time. My taxi driver had a .45 automatic gun in his car and showed it to me. Plus he had extra ammunition. That didn't make me feel more safe though I can use a pistol and trained with some. But as a girl things have maybe a different vibe in some areas.